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How to get rid of acne: a step by step plan

To get rid of acne, put adapalene, benzoyl peroxide or both on all acne-prone skin every day for 12 weeks, and see a doctor for deep or scarring acne.

A plain white pump bottle, a white tube, a folded towel and a glass of water on a shelf by a sunny window

Written for Skinli by Nick, Founder of Skinli. Not a doctor. General education only. How these guides are written.

Checked against Journal of the American Academy of Dermatology, PubMed record, National Institute for Health and Care Excellence (NICE), American Academy of Dermatology, Electronic Code of Federal Regulations, for the FDA. See every source.

To get rid of acne, use a treatment with strong evidence, such as benzoyl peroxide, adapalene, or the two together, on all the skin that breaks out, every day, for 12 weeks. Then keep it going, add a second treatment, or see a doctor. This page walks through each step in order, based on the 2024 acne guideline from the American Academy of Dermatology (AAD) and the UK guideline from NICE, which advises doctors in England. Deep, painful or scarring acne needs a dermatologist, and the last step explains when.

Step 1: Find out what type of acne you have

The AAD says it helps to know which types of blemishes you have, because each type needs different treatment. You can do a first check in a mirror, in daylight.

What you seeWhat it isWhere to start
Small bumps, white or dark tops, little rednessWhiteheads and blackheads (clogged pores)A retinoid such as adapalene, or salicylic acid
Red, tender bumps, some with pusPapules and pustules (inflamed spots)Benzoyl peroxide, often with adapalene
Large, painful lumps deep in the skinNodules and cystsA dermatologist

NICE also sorts acne by count. Mild to moderate acne means any number of blackheads and whiteheads, up to 34 inflamed spots, and up to 2 nodules. Moderate to severe means 35 or more inflamed spots, or 3 or more nodules. A store routine is built for the first group. Types of acne shows each spot in more detail. What is acne explains how a clogged pore turns into a pimple.

Step 2: Start a proven treatment, or the proven pair

The 2024 AAD guideline gives its strongest rating to benzoyl peroxide, topical retinoids, topical antibiotics and oral doxycycline. Salicylic acid and azelaic acid get a conditional rating, one step lower. Two of the strongest are sold without a prescription in the US:

Salicylic acid is allowed at 0.5 to 2 percent.

You can start one of these, or both together. The two work on different causes of acne. The AAD says benzoyl peroxide is most effective when used along with another acne treatment that works on the other causes, such as a retinoid. NICE lists a combination of adapalene and benzoyl peroxide as a first choice for acne of any severity, and the 2024 AAD guideline lists combining treatments that work in different ways as good practice. NICE means one gel that holds both. In the US, each is sold without a prescription as its own gel.

Whichever you choose, keep it simple. AAD dermatologists advise using your treatment for 6 to 8 weeks without adding another product or stopping. Every store acne label also warns that irritation is more likely when you use another acne medicine on the skin at the same time, so leave out extra acne products such as a salicylic acid toner.

The best acne treatments by guideline ranks every option by its evidence, over-the-counter acne treatments shows how to read a Drug Facts box in a store, and acne serums explains how to judge a serum by its active ingredient. For the choice between the two most common store ingredients, see salicylic acid vs benzoyl peroxide.

Step 3: Use it the right way

How you apply a treatment matters as much as which one you pick.

  1. Whole area, thin layer. AAD dermatologist Dr. Harper says to apply a thin layer to the whole area rather than only the spots. Medicine only on the spots you see treats them but does not prevent the next ones.
  2. Start slowly. NICE says to start benzoyl peroxide and retinoids every other day, or to wash them off after an hour, and to move to normal use once the skin copes. The FDA directions for store acne products say to start with one application a day.
  3. Once a day for adapalene. Its label says using it more often will not give faster or better results but may worsen irritation.
  4. Moisturize. The AAD says acne treatments tend to dry and irritate the skin, and a daily moisturizer helps skin tolerate them.
  5. Cut back, do not quit. If dryness or peeling bothers you, the FDA directions say to reduce to once a day or every other day.

How to start adapalene without irritation walks through the first weeks of a retinoid, and what order to apply acne products shows where each gel goes at night.

Step 4: Protect your skin while treatment works

These habits come from the AAD and NICE:

NICE says there is not enough evidence to support specific diets for treating acne. How to get rid of acne naturally covers what research shows about diet, tea tree oil and home remedies. The US National Center for Complementary and Integrative Health says only a small amount of evidence suggests tea tree oil might help acne. The acne skincare routine puts every product in order.

Step 5: Give it 12 weeks

Each source gives its own timeline, and they agree that acne treatment takes weeks, not days.

SourceTimeline
AAD, 10 skin care habits that can worsen acneUse a product for 6 to 8 weeks to see some improvement. Complete clearing generally takes 3 to 4 months
AAD, adult acne treatmentIf the medicine works: fewer breakouts in 4 to 8 weeks, clearing 16 weeks after starting
NHS, benzoyl peroxideUsually starts to work within 4 weeks
Adapalene labelMay take up to 3 months of once daily use to see results
NICEPositive effects can take 6 to 8 weeks to show. Review the first treatment at 12 weeks

The adapalene label also says that during the early weeks of use acne may look worse before it improves, and calls this normal. How to get rid of acne fast covers what helps treatment work as soon as it can, and how long an acne routine takes to work covers what to look for at each week.

Step 6: Add a second treatment, or see a doctor

If one product has not helped after 4 to 6 weeks, the AAD suggests adding a second product that works on a different cause. If you use benzoyl peroxide, the second might be adapalene. Add it slowly, every other night at first.

See a doctor if any of these apply:

A dermatologist can prescribe creams, antibiotic pills paired with benzoyl peroxide, hormone treatments for women, and isotretinoin for severe acne. The AAD says 85 percent of patients see permanent clearing after one course of isotretinoin. Severe acne and when to see a dermatologist covers each option, and how to get rid of hormonal acne covers the hormone treatments.

Single pimples, adults and scars

Some questions fall outside the six steps.

Brown and black skin

On darker skin, acne often leaves marks that last longer than the spots. AAD dermatologists say that dark spots after acne clears develop more often in people with darker skin tones, and that they show the acne is causing a lot of inflammation, which products bought without a prescription usually cannot control. They advise seeing a dermatologist when these marks appear. The AAD also says raised acne scars are more common in people with darker skin tones. Three steps from this plan matter most here: start treatment early, keep your hands off, and wear sunscreen every day.

Teens and pregnancy

The 2024 AAD guideline covers acne in adults, teens and children from age 9. Adapalene 0.1 percent gel is approved without a prescription for ages 12 and older. Retinoids for teens covers what the labels say for younger users.

Pregnancy changes the plan. AAD dermatologist Ramone Williams, MD, says to consult a dermatologist before treating acne on your own if you are pregnant or trying to get pregnant. NICE says topical retinoids, including adapalene, should not be used during pregnancy or while planning one.

Keep acne away after it clears

Clear skin is a reason to keep going. The AAD says to keep using the acne treatment even when you see clearing, to help prevent new breakouts, and that dermatologists may recommend a topical retinoid as maintenance. For people whose acne often returns, NICE suggests a combination of adapalene and benzoyl peroxide as maintenance, reviewed after 12 weeks.

Skinli's plan follows these steps with the pair: adapalene 0.1 percent gel and benzoyl peroxide 2.5 percent gel at night, every other night for the first 2 weeks and then every night, with a gentle wash, moisturizer and SPF 30 sunscreen. The sample plan shows it day by day.

Guides on treatments, single pimples, scars and doctor care

Choosing a treatment

Treating pimples

Doctor care and scars

Frequently asked questions

How to get rid of acne?

Acne clears best with benzoyl peroxide, adapalene, or the two together, used every day on the whole area that breaks out for 12 weeks. The American Academy of Dermatology's 2024 guideline gives its strongest rating to benzoyl peroxide and topical retinoids such as adapalene, and the UK NICE guideline lists adapalene combined with benzoyl peroxide as a first choice. Deep, painful or scarring acne needs a dermatologist.

Can acne be cured?

Acne can be controlled in almost everyone with treatment, and the American Academy of Dermatology says that with a dermatologist's help virtually everyone can see clearer skin. Acne can return when treatment stops. The AAD says to keep using treatment after the skin clears, and the UK NICE guideline suggests maintenance treatment for people whose acne often comes back.

What stops acne?

Acne is stopped by treatments that work on its causes: extra oil, clogged pores, bacteria and inflammation. The American Academy of Dermatology says benzoyl peroxide reduces acne bacteria and works best with a second treatment, and that retinoids such as adapalene clear pores. It says a thin layer over all acne-prone skin helps prevent new breakouts, while putting medicine only on visible spots leaves new ones untreated.

How to get rid of acne on face?

Acne on the face is treated with a thin layer of one acne ingredient over the whole area that breaks out, such as the forehead, nose and chin, according to the American Academy of Dermatology. Wash twice a day with a gentle cleanser and your fingertips, use products labeled non-comedogenic, and wear SPF 30 sunscreen. The AAD says to expect fewer breakouts in 4 to 8 weeks.

How to get rid of acne that won't go away?

Acne that will not go away after 4 to 6 weeks of one treatment may need a second product that works on a different cause, the American Academy of Dermatology says. If it still has not cleared, see a doctor. The UK NICE guideline advises considering a dermatologist referral for mild to moderate acne that has not responded to two completed 12-week courses of treatment.

How to get rid of acne completely?

Clearing acne completely takes 3 to 4 months of steady treatment in most cases, according to the American Academy of Dermatology. The AAD's adult acne guidance puts clearing at 16 weeks after starting a medicine that works. For severe acne, it says 85 percent of patients see permanent clearing after one course of isotretinoin, a prescription pill that takes four to five months.

How to get rid of acne as a teenager?

Teen acne is treated with the same proven ingredients as adult acne, and the 2024 American Academy of Dermatology guideline covers people aged 9 and older. Adapalene 0.1 percent gel is FDA approved without a prescription for ages 12 and up. Start one product or the adapalene and benzoyl peroxide pair, use a thin layer on the whole area, and see a doctor for deep, painful or scarring acne.

How to get rid of acne without medication?

Mild acne can improve with habits alone: washing twice a day and after sweating, no scrubbing, keeping hands off, using non-comedogenic products and removing makeup before bed, all advised by the American Academy of Dermatology. Tea tree oil has only a small amount of research behind it, says the US National Center for Complementary and Integrative Health. Most acne still needs an acne treatment to clear.

How to get rid of acne during pregnancy?

Acne during pregnancy should be treated with a doctor's advice, because the American Academy of Dermatology says some acne treatments sold without a prescription are not safe in pregnancy. The UK NICE guideline says topical retinoids, including adapalene, and tetracycline antibiotic pills should not be used during pregnancy. NICE lists a benzoyl peroxide and clindamycin gel as one that can be used with caution.

How to get rid of acne forever?

Acne can stay away long term with maintenance treatment after it clears. The American Academy of Dermatology says to keep using acne treatment once the skin clears, and says dermatologists may recommend a topical retinoid to keep skin clear. The UK NICE guideline suggests a combination of adapalene and benzoyl peroxide as a maintenance option, reviewed every 12 weeks.

What is the first step to get rid of acne?

The first step to get rid of acne is to look at which types of spots you have, because the American Academy of Dermatology says different types of acne often need different treatment. Blackheads and whiteheads respond to a retinoid such as adapalene, red pimples to benzoyl peroxide, and deep, painful lumps need a dermatologist. Then start the treatment and add nothing else new.

Sources

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Skinli gives simple tips for skin with pimples. It is not a doctor. It cannot tell you what is wrong the way a doctor can. If your pimples hurt, are deep under the skin, are getting worse, or will not go away, see a doctor.