September 25, 2026
How to get rid of acne: a step by step plan
A six-step acne plan built from the US and UK guidelines: find your acne type, pick one proven treatment, use it right, give it 12 weeks, then add or refer.
By Nick, Founder of Skinli. Not a doctor. General education only.
Getting rid of acne follows the same pattern for most people: find out what type you have, start one treatment with good evidence, use it the right way, give it 12 weeks, and then add a second treatment or see a doctor. This page walks through each step, based on the 2024 acne guideline from the American Academy of Dermatology (AAD) and the UK guideline from NICE, which advises doctors in England. Skinli is education and is not a doctor. Deep, painful or scarring acne needs a dermatologist, and the last step explains when.
Step 1: Find out what type of acne you have
The AAD says a dermatologist diagnoses acne by looking at the breakouts, and that different types of acne often need different treatment. You can do a first check in a mirror, in daylight.
| What you see | What it is | Where to start |
|---|---|---|
| Small bumps, white or dark tops, little redness | Whiteheads and blackheads (clogged pores) | A retinoid such as adapalene, or salicylic acid |
| Red, tender bumps, some with pus | Papules and pustules (inflamed spots) | Benzoyl peroxide, or a wash with benzoyl peroxide or salicylic acid |
| Large, painful lumps deep in the skin | Nodules and cysts | A dermatologist |
NICE also sorts acne by count. Mild to moderate acne means any number of blackheads and whiteheads, up to 34 inflamed spots, and up to 2 nodules. Moderate to severe means 35 or more inflamed spots, or 3 or more nodules. A store routine is built for the first group.
Step 2: Start one proven treatment
The 2024 AAD guideline gives its strongest rating to benzoyl peroxide, topical retinoids, topical antibiotics and oral doxycycline. Salicylic acid and azelaic acid get a conditional rating, one step lower. Two of the strongest are sold without a prescription in the US:
- Benzoyl peroxide, which reduces acne-causing bacteria. The FDA allows 2.5 to 10 percent. The AAD advises starting at 2.5 percent.
- Adapalene 0.1 percent gel, a retinoid that clears pores. The FDA approved it without a prescription in 2016 for ages 12 and up.
Salicylic acid, allowed at 0.5 to 2 percent, works best on whiteheads and blackheads, the AAD says.
Start one. AAD dermatologists advise using one product for 6 to 8 weeks without adding or stopping others, because the FDA requires every acne label to warn that irritation is more likely when two acne medicines are used together.
The best acne treatments by guideline compares every option, over-the-counter acne treatments shows how to read a Drug Facts box, and acne serums explains how to judge a serum by its active ingredient. For the choice between the two most common store ingredients, see salicylic acid vs benzoyl peroxide.
Step 3: Use it the right way
How you apply a treatment matters as much as which one you pick.
- Whole area, thin layer. The AAD says to spread a thin layer over all acne-prone skin. Putting medicine only on the spots you see treats them but fails to prevent new ones.
- Start slowly. The FDA directions say to start with one application a day. NICE says to start benzoyl peroxide and retinoids every other day, or to wash them off after an hour, and to move to normal use once the skin copes.
- Once a day for adapalene. Its label says using it more often will not give faster or better results but may worsen irritation.
- Moisturize. The AAD says acne treatments tend to dry and irritate the skin, and a daily moisturizer helps skin tolerate them.
- Cut back, do not quit. If dryness or peeling bothers you, the FDA label says to reduce to once a day or every other day.
How to start adapalene without irritation walks through the first weeks of a retinoid.
Step 4: Protect your skin while treatment works
These habits come from the AAD, the NHS and NICE:
- Wash gently, twice a day and after sweating. Use a mild cleanser and fingertips. The AAD says scrubbing irritates acne-prone skin and makes acne flare.
- Keep your hands off. The AAD says picking and popping make acne take longer to clear and raise the risk of scars and dark spots. NICE says persistent picking can increase the risk of scarring.
- Check your products. Use makeup, sunscreen, moisturizer and hair products labeled non-comedogenic or won't clog pores, and remove makeup before bed.
- Skip drying products. The AAD warns against astringents, toners and exfoliants.
- Wear sunscreen. Some acne medicines make skin more sensitive to the sun. The AAD advises a broad-spectrum, water-resistant sunscreen of SPF 30 or higher labeled non-comedogenic.
NICE says there is not enough evidence to support specific diets for treating acne. How to get rid of acne naturally covers what research shows about diet, tea tree oil and home remedies, and the complete acne skincare routine puts every product in order.
Step 5: Give it 12 weeks
| Source | Timeline |
|---|---|
| AAD | At least 6 to 8 weeks before fewer breakouts. Complete clearing generally takes 3 to 4 months |
| AAD, adult acne | Fewer breakouts in 4 to 8 weeks. Clearing 16 weeks after starting |
| NHS | Benzoyl peroxide usually starts to work within 4 weeks |
| Adapalene label | Up to 3 months of once-daily use to see results |
| NICE | Review the first treatment at 12 weeks |
The adapalene label also says acne may look worse in the early weeks before it improves, and calls this normal. How to get rid of acne fast covers what helps treatment work as soon as it can, and how long an acne routine takes to work covers what to look for at each week.
Step 6: Add a second treatment, or see a doctor
If one product has not helped after 4 to 6 weeks, the AAD suggests adding a second product that works on a different cause. If you use benzoyl peroxide, the second might be adapalene. Add it slowly.
See a doctor if any of these apply, per the AAD, NICE and the NHS:
- Deep, painful lumps (nodules or cysts), at any point
- Acne that leaves scars, or dark marks that stay
- Mild to moderate acne that has not responded to two full 12-week courses
- Acne that affects your mood or mental health
- Hot, swollen, red skin around spots, a sign of skin infection
A dermatologist can prescribe creams, antibiotic pills paired with benzoyl peroxide, hormone treatments for women, and isotretinoin for severe acne. Severe acne and when to see a dermatologist covers each option.
Single pimples, adults and scars
Some questions fall outside the six steps.
- One pimple, now. How to get rid of pimples covers each type of spot, acne spot treatment and pimple patches cover single-spot products, and can you get rid of a pimple overnight? covers what one night can do.
- Acne after the teen years. Adult acne covers the causes the AAD lists, from hormones to hair products.
- Scars. How to get rid of acne scars covers what creams and dermatologist procedures can do.
Brown and black skin
On darker skin, acne often leaves marks that last longer than the spots. AAD dermatologists say dark spots after acne clears are more common in people with darker skin tones, and that they show the acne is causing a lot of inflammation, which products bought without a prescription usually cannot control. They advise seeing a dermatologist when these marks appear. The AAD also says raised scars are more common on darker skin, and that squeezing a deep pimple raises the risk of discoloration. Three steps from this plan matter most here: start treatment early, keep your hands off, and wear sunscreen every day.
Teens and pregnancy
The 2024 AAD guideline covers acne in adults, teens and children from age 9. Adapalene 0.1 percent gel is approved without a prescription for ages 12 and older. Retinoids for teens covers what the labels say for younger users.
Pregnancy changes the plan. AAD dermatologist Ramone Williams, MD, says to consult a dermatologist before treating acne on your own if you are pregnant or trying to get pregnant. NICE says topical retinoids, including adapalene, should not be used during pregnancy or while planning one.
Keep acne away after it clears
Clear skin is a reason to keep going. The AAD says to keep using acne treatment after you see clearing, to help prevent new breakouts, and that dermatologists may recommend a topical retinoid as maintenance. For people whose acne often returns, NICE suggests considering a combination of adapalene and benzoyl peroxide as maintenance, reviewed every 12 weeks.
Skinli's plan follows these steps. It uses the two gels NICE names first for acne of any severity, adapalene 0.1 percent and benzoyl peroxide 2.5 percent, starts them every other night for two weeks, and asks for 12 weeks before judging the result.
Guides on treatments, single pimples, scars and doctor care
Choosing a treatment
- Best acne treatments, according to the guidelinesWhich acne treatments the 2024 US guideline and the UK NICE guideline rate highest, which ones fit which type of acne, and when the best choice needs a doctor.
- Over-the-counter acne treatments: what to buyThe acne ingredients the FDA allows without a prescription, the legal strength of each, how to read the Drug Facts label, and how long to give one.
- Acne serums: how to read the label firstAn acne serum is a format, and the active ingredient decides what it does. How to check the Drug Facts box, when to apply a serum, and what to avoid mixing.
- How to get rid of acne naturally: the evidenceWhat the research says about tea tree oil, diet and other natural acne remedies, where the evidence is weak, and the no-product habits that do help.
- How to get rid of acne fast: realistic timelinesHow fast acne treatments work, the steps that help them work sooner, the habits that slow clearing down, and the doctor options that act within days.
Treating pimples
- How to get rid of pimples without popping themHow to treat a red pimple, a pus-filled spot or a deep, painful lump at home, why popping slows healing, and which pimples need a doctor.
- Acne spot treatment: when dabbing one pimple helpsWhat an acne spot treatment can and cannot do, which ingredients work on a single pimple, why the labels ask for the whole area, and how to avoid irritation.
- Pimple patches: what they do and when they helpWhat hydrocolloid pimple patches do, what the one small trial found, which pimples they suit, and why deep, painful acne needs something else.
- Can you get rid of a pimple overnight?What one night can and cannot do for a pimple, the safe steps for tonight, why toothpaste and popping hurt, and the doctor treatment that works in days.
Doctor care and scars
- Severe acne: when to see a dermatologistHow doctors define severe acne, the signs that mean a store routine is not enough, what a dermatologist can prescribe, and how to prepare for the visit.
- Adult acne: causes and what helpsWhy adults in their 20s to 50s still get acne, the common causes the AAD lists, the treatments that fit adult skin, and when to see a dermatologist.
- How to get rid of acne scars: what worksSunken and raised acne scars rarely go away alone. What retinoids and salicylic acid can do at home, what dermatologists use, and how to prevent new scars.
Frequently asked questions
How to get rid of acne?
Acne clears best with one proven treatment used every day on the whole area that breaks out, for at least 12 weeks. The American Academy of Dermatology's 2024 guideline gives its strongest rating to benzoyl peroxide and topical retinoids such as adapalene, both sold without a prescription. The AAD says fewer breakouts take 6 to 8 weeks. Deep, painful or scarring acne needs a dermatologist.
Can acne be cured?
Acne can be controlled in almost everyone with treatment, and the American Academy of Dermatology says that with a dermatologist's help virtually every case of acne can be cleared. Acne can return when treatment stops. The AAD says to keep using treatment after the skin clears, and the UK NICE guideline suggests maintenance treatment for people whose acne often comes back.
What stops acne?
Acne is stopped by treatments that work on its causes: extra oil, clogged pores, bacteria and inflammation. The American Academy of Dermatology says benzoyl peroxide reduces acne bacteria and retinoids such as adapalene unclog pores and reduce oiliness. It says a thin layer over all acne-prone skin helps prevent new breakouts, while putting medicine only on visible spots leaves new ones untreated.
How to get rid of acne on face?
Acne on the face is treated with a thin layer of one acne ingredient over the whole area that breaks out, such as the forehead, nose and chin, according to the American Academy of Dermatology. Wash twice a day with a gentle cleanser and your fingertips, use products labeled non-comedogenic, and wear SPF 30 sunscreen. The AAD says to expect fewer breakouts in 4 to 8 weeks.
How to get rid of acne that won't go away?
Acne that will not go away after 4 to 6 weeks of one treatment may need a second product that works on a different cause, the American Academy of Dermatology says. If it still has not cleared, see a doctor. The UK NICE guideline advises considering a dermatologist referral for mild to moderate acne that has not responded to two completed 12-week courses of treatment.
How to get rid of acne completely?
Clearing acne completely takes 3 to 4 months of steady treatment in most cases, according to the American Academy of Dermatology. The AAD's adult acne guidance puts clearing at 16 weeks after starting a medicine that works. For severe acne, it says 85 percent of patients see permanent clearing after one course of isotretinoin, a prescription pill that takes four to five months.
How to get rid of acne as a teenager?
Teen acne is treated with the same proven ingredients as adult acne, and the 2024 American Academy of Dermatology guideline covers people aged 9 and older. Adapalene 0.1 percent gel is FDA approved without a prescription for ages 12 and up. Start one product, use a thin layer on the whole area, and see a doctor for deep, painful or scarring acne.
How to get rid of acne without medication?
Mild acne can improve with habits alone: washing twice a day and after sweating, no scrubbing, keeping hands off, using non-comedogenic products and removing makeup before bed, all advised by the American Academy of Dermatology. Tea tree oil has only a small amount of research behind it, says the US National Center for Complementary and Integrative Health. Most acne still needs an acne treatment to clear.
How to get rid of acne during pregnancy?
Acne during pregnancy should be treated with a doctor's advice, because the American Academy of Dermatology says some acne treatments sold without a prescription are not safe in pregnancy. The UK NICE guideline says topical retinoids, including adapalene, and tetracycline antibiotic pills should not be used during pregnancy. NICE lists a benzoyl peroxide and clindamycin gel as one that can be used with caution.
How to get rid of acne forever?
Acne can stay away long term with maintenance treatment after it clears. The American Academy of Dermatology says to keep using acne treatment once the skin clears, and says dermatologists may recommend a topical retinoid to keep skin clear. The UK NICE guideline suggests a combination of adapalene and benzoyl peroxide as a maintenance option, reviewed every 12 weeks.
What is the first step to get rid of acne?
The first step to get rid of acne is to look at which types of spots you have, because the American Academy of Dermatology says different types of acne often need different treatment. Blackheads and whiteheads respond to a retinoid such as adapalene, red pimples to benzoyl peroxide, and deep, painful lumps need a dermatologist. Then start one product at a time.
Sources
- Guidelines of care for the management of acne vulgaris (Journal of the American Academy of Dermatology, PubMed record)
- Acne vulgaris: management (NG198), Recommendations (National Institute for Health and Care Excellence (NICE))
- Acne: Diagnosis and treatment (American Academy of Dermatology)
- Adult acne treatment dermatologists recommend (American Academy of Dermatology)
- 9 things to try when acne won't clear (American Academy of Dermatology)
- 10 skin care habits that can worsen acne (American Academy of Dermatology)
- 6 skin care habits that can clear acne (American Academy of Dermatology)
- How to treat different types of acne (American Academy of Dermatology)
- What can clear severe acne? (American Academy of Dermatology)
- 21 CFR Part 333 Subpart D, Topical Acne Drug Products (Electronic Code of Federal Regulations, for the FDA)
- Differin Gel (adapalene), 0.1%, supplement approval letter, NDA 20380/S-010 (FDA Center for Drug Evaluation and Research)
- DIFFERIN (adapalene) gel, Human OTC Drug Label (DailyMed, U.S. National Library of Medicine (label: Galderma Laboratories, L.P.))
- Acne (NHS)
- Tea Tree Oil: Usefulness and Safety (National Center for Complementary and Integrative Health (NIH))
- Moisturizer: Why you may need it if you have acne (American Academy of Dermatology)
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Analyze my skinSkinli gives simple tips for skin with pimples. It is not a doctor. It cannot tell you what is wrong the way a doctor can. If your pimples hurt, are deep under the skin, are getting worse, or will not go away, see a doctor.