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How to get rid of acne: a step by step plan
To get rid of acne, put adapalene, benzoyl peroxide or both on all acne-prone skin every day for 12 weeks, and see a doctor for deep or scarring acne.
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Written for Skinli by Nick, Founder of Skinli. Not a doctor. General education only. How these guides are written.
Checked against Journal of the American Academy of Dermatology, PubMed record, National Institute for Health and Care Excellence (NICE), American Academy of Dermatology, Electronic Code of Federal Regulations, for the FDA. See every source.
To get rid of acne, use a treatment with strong evidence, such as benzoyl peroxide, adapalene, or the two together, on all the skin that breaks out, every day, for 12 weeks. Then keep it going, add a second treatment, or see a doctor. This page walks through each step in order, based on the 2024 acne guideline from the American Academy of Dermatology (AAD) and the UK guideline from NICE, which advises doctors in England. Deep, painful or scarring acne needs a dermatologist, and the last step explains when.
Step 1: Find out what type of acne you have
The AAD says it helps to know which types of blemishes you have, because each type needs different treatment. You can do a first check in a mirror, in daylight.
| What you see | What it is | Where to start |
|---|---|---|
| Small bumps, white or dark tops, little redness | Whiteheads and blackheads (clogged pores) | A retinoid such as adapalene, or salicylic acid |
| Red, tender bumps, some with pus | Papules and pustules (inflamed spots) | Benzoyl peroxide, often with adapalene |
| Large, painful lumps deep in the skin | Nodules and cysts | A dermatologist |
NICE also sorts acne by count. Mild to moderate acne means any number of blackheads and whiteheads, up to 34 inflamed spots, and up to 2 nodules. Moderate to severe means 35 or more inflamed spots, or 3 or more nodules. A store routine is built for the first group. Types of acne shows each spot in more detail. What is acne explains how a clogged pore turns into a pimple.
Step 2: Start a proven treatment, or the proven pair
The 2024 AAD guideline gives its strongest rating to benzoyl peroxide, topical retinoids, topical antibiotics and oral doxycycline. Salicylic acid and azelaic acid get a conditional rating, one step lower. Two of the strongest are sold without a prescription in the US:
- Benzoyl peroxide, which reduces acne-causing bacteria. The FDA allows 2.5 to 10 percent in store products. AAD dermatologists advise starting at 2.5 percent to avoid dry, irritated or burning skin.
- Adapalene 0.1 percent gel, a retinoid that clears pores. The FDA approved it without a prescription in 2016 for ages 12 and up.
Salicylic acid is allowed at 0.5 to 2 percent.
You can start one of these, or both together. The two work on different causes of acne. The AAD says benzoyl peroxide is most effective when used along with another acne treatment that works on the other causes, such as a retinoid. NICE lists a combination of adapalene and benzoyl peroxide as a first choice for acne of any severity, and the 2024 AAD guideline lists combining treatments that work in different ways as good practice. NICE means one gel that holds both. In the US, each is sold without a prescription as its own gel.
Whichever you choose, keep it simple. AAD dermatologists advise using your treatment for 6 to 8 weeks without adding another product or stopping. Every store acne label also warns that irritation is more likely when you use another acne medicine on the skin at the same time, so leave out extra acne products such as a salicylic acid toner.
The best acne treatments by guideline ranks every option by its evidence, over-the-counter acne treatments shows how to read a Drug Facts box in a store, and acne serums explains how to judge a serum by its active ingredient. For the choice between the two most common store ingredients, see salicylic acid vs benzoyl peroxide.
Step 3: Use it the right way
How you apply a treatment matters as much as which one you pick.
- Whole area, thin layer. AAD dermatologist Dr. Harper says to apply a thin layer to the whole area rather than only the spots. Medicine only on the spots you see treats them but does not prevent the next ones.
- Start slowly. NICE says to start benzoyl peroxide and retinoids every other day, or to wash them off after an hour, and to move to normal use once the skin copes. The FDA directions for store acne products say to start with one application a day.
- Once a day for adapalene. Its label says using it more often will not give faster or better results but may worsen irritation.
- Moisturize. The AAD says acne treatments tend to dry and irritate the skin, and a daily moisturizer helps skin tolerate them.
- Cut back, do not quit. If dryness or peeling bothers you, the FDA directions say to reduce to once a day or every other day.
How to start adapalene without irritation walks through the first weeks of a retinoid, and what order to apply acne products shows where each gel goes at night.
Step 4: Protect your skin while treatment works
These habits come from the AAD and NICE:
- Wash gently, twice a day and after sweating. The AAD says to use a gentle cleanser and your fingertips, because scrubbing with washcloths and sponges can irritate the skin.
- Keep your hands off. NICE says persistent picking can increase the risk of scarring.
- Check your products. The AAD says to use only makeup, sunscreen, skin and hair products labeled non-comedogenic or won't clog pores. The comedogenic checker looks up the ingredients on a label.
- Skip drying products. The AAD warns against astringents, toners and exfoliants, which can dry the skin and make acne look worse.
- Wear sunscreen. The AAD advises a broad-spectrum, water-resistant sunscreen of SPF 30 or higher that says non-comedogenic.
NICE says there is not enough evidence to support specific diets for treating acne. How to get rid of acne naturally covers what research shows about diet, tea tree oil and home remedies. The US National Center for Complementary and Integrative Health says only a small amount of evidence suggests tea tree oil might help acne. The acne skincare routine puts every product in order.
Step 5: Give it 12 weeks
Each source gives its own timeline, and they agree that acne treatment takes weeks, not days.
| Source | Timeline |
|---|---|
| AAD, 10 skin care habits that can worsen acne | Use a product for 6 to 8 weeks to see some improvement. Complete clearing generally takes 3 to 4 months |
| AAD, adult acne treatment | If the medicine works: fewer breakouts in 4 to 8 weeks, clearing 16 weeks after starting |
| NHS, benzoyl peroxide | Usually starts to work within 4 weeks |
| Adapalene label | May take up to 3 months of once daily use to see results |
| NICE | Positive effects can take 6 to 8 weeks to show. Review the first treatment at 12 weeks |
The adapalene label also says that during the early weeks of use acne may look worse before it improves, and calls this normal. How to get rid of acne fast covers what helps treatment work as soon as it can, and how long an acne routine takes to work covers what to look for at each week.
Step 6: Add a second treatment, or see a doctor
If one product has not helped after 4 to 6 weeks, the AAD suggests adding a second product that works on a different cause. If you use benzoyl peroxide, the second might be adapalene. Add it slowly, every other night at first.
See a doctor if any of these apply:
- Deep, painful lumps (nodules or cysts), at any point. NICE refers nodulo-cystic acne to a specialist.
- Acne that leaves scars, or dark marks that stay (NICE)
- Mild to moderate acne that has not responded to two completed 12-week courses
- Acne that affects your mood or mental health (NICE)
- Acne that is not clearing within a few months of your own treatment, the point where AAD dermatologist Dr. Harper says to make an appointment
A dermatologist can prescribe creams, antibiotic pills paired with benzoyl peroxide, hormone treatments for women, and isotretinoin for severe acne. The AAD says 85 percent of patients see permanent clearing after one course of isotretinoin. Severe acne and when to see a dermatologist covers each option, and how to get rid of hormonal acne covers the hormone treatments.
Single pimples, adults and scars
Some questions fall outside the six steps.
- One pimple, now. How to get rid of pimples covers each type of spot, acne spot treatment and pimple patches cover single-spot products, and can you get rid of a pimple overnight? covers what one night can do.
- Acne after the teen years. Adult acne covers the causes the AAD lists, from hormones to hair products.
- Scars. How to get rid of acne scars covers what creams and dermatologist procedures can do.
- Apps and online services. If you are choosing between an app, an online doctor service and a store routine, the comparison pages set them side by side.
Brown and black skin
On darker skin, acne often leaves marks that last longer than the spots. AAD dermatologists say that dark spots after acne clears develop more often in people with darker skin tones, and that they show the acne is causing a lot of inflammation, which products bought without a prescription usually cannot control. They advise seeing a dermatologist when these marks appear. The AAD also says raised acne scars are more common in people with darker skin tones. Three steps from this plan matter most here: start treatment early, keep your hands off, and wear sunscreen every day.
Teens and pregnancy
The 2024 AAD guideline covers acne in adults, teens and children from age 9. Adapalene 0.1 percent gel is approved without a prescription for ages 12 and older. Retinoids for teens covers what the labels say for younger users.
Pregnancy changes the plan. AAD dermatologist Ramone Williams, MD, says to consult a dermatologist before treating acne on your own if you are pregnant or trying to get pregnant. NICE says topical retinoids, including adapalene, should not be used during pregnancy or while planning one.
Keep acne away after it clears
Clear skin is a reason to keep going. The AAD says to keep using the acne treatment even when you see clearing, to help prevent new breakouts, and that dermatologists may recommend a topical retinoid as maintenance. For people whose acne often returns, NICE suggests a combination of adapalene and benzoyl peroxide as maintenance, reviewed after 12 weeks.
Skinli's plan follows these steps with the pair: adapalene 0.1 percent gel and benzoyl peroxide 2.5 percent gel at night, every other night for the first 2 weeks and then every night, with a gentle wash, moisturizer and SPF 30 sunscreen. The sample plan shows it day by day.
Guides on treatments, single pimples, scars and doctor care
Choosing a treatment
- Best acne treatments, according to the guidelinesThe best-rated acne treatments are benzoyl peroxide and retinoids such as adapalene, and the UK guideline's first choice for any acne combines the two.
- Over-the-counter acne treatments: what to buyThe acne medicines you can buy without a prescription are benzoyl peroxide, salicylic acid, sulfur and adapalene 0.1% gel. Check the Drug Facts box for them.
- Acne serums: how to read the label firstAn acne serum works only if its Drug Facts box lists an acne ingredient, such as salicylic acid 0.5 to 2% or benzoyl peroxide 2.5 to 10%, at a legal strength.
- How to get rid of acne naturally: the evidenceTea tree oil is the best-studied natural acne remedy, but its evidence is weak, and most acne still needs benzoyl peroxide or adapalene to clear.
- How to get rid of acne fast: realistic timelinesThe fastest way to clear acne still takes 6 to 8 weeks: use a proven treatment on all acne-prone skin every day and do not switch products or pick.
- Sulfur for acne: what it does and how to use itThe FDA allows sulfur at 3 to 10 percent in acne products sold without a prescription. How masks and spot products are used, side effects, and how it compares.
- LED light therapy for acne: blue, red and masksBlue and red LED light can treat pimples, and the AAD says it does not work on blackheads, whiteheads or cysts. Rarely does light alone clear acne.
Treating pimples
- How to get rid of pimples without popping themTo get rid of pimples, keep your hands off them and treat the whole area with benzoyl peroxide or salicylic acid. Deep, painful lumps need a doctor.
- Acne spot treatment: when dabbing one pimple helpsA spot treatment helps one pimple on clear skin once it reaches the surface, but acne that keeps coming back needs a thin layer on the whole area instead.
- Pimple patches: what they do and when they helpPimple patches help one surface pimple heal and stop you picking it, based on one small 2006 trial, but they do not work on deep, painful acne.
- Can you get rid of a pimple overnight?No home treatment clears a pimple overnight, but ice, benzoyl peroxide and a patch help, and a doctor's injection flattens most cysts in 48 to 72 hours.
Doctor care and scars
- Severe acne: when to see a dermatologistSee a dermatologist for deep, painful lumps, scars or dark marks, acne that store products have not cleared, or acne that affects your mood.
- Adult acne: causes and what helpsAdults get acne from hormone changes, stress, family history, pore-clogging products, medicines or an illness, and mild cases often clear with store products.
- How to get rid of acne scars: what worksAcne scars can fade but rarely go away, and a dermatologist can make them less noticeable with peels, laser, microneedling, fillers or minor surgery.
- Doxycycline for acne: how it works and how longDoxycycline is an antibiotic pill for red, inflamed acne. What the 2024 AAD guideline and the drug label say on course length, side effects and isotretinoin.
Frequently asked questions
How to get rid of acne?
Acne clears best with benzoyl peroxide, adapalene, or the two together, used every day on the whole area that breaks out for 12 weeks. The American Academy of Dermatology's 2024 guideline gives its strongest rating to benzoyl peroxide and topical retinoids such as adapalene, and the UK NICE guideline lists adapalene combined with benzoyl peroxide as a first choice. Deep, painful or scarring acne needs a dermatologist.
Can acne be cured?
Acne can be controlled in almost everyone with treatment, and the American Academy of Dermatology says that with a dermatologist's help virtually everyone can see clearer skin. Acne can return when treatment stops. The AAD says to keep using treatment after the skin clears, and the UK NICE guideline suggests maintenance treatment for people whose acne often comes back.
What stops acne?
Acne is stopped by treatments that work on its causes: extra oil, clogged pores, bacteria and inflammation. The American Academy of Dermatology says benzoyl peroxide reduces acne bacteria and works best with a second treatment, and that retinoids such as adapalene clear pores. It says a thin layer over all acne-prone skin helps prevent new breakouts, while putting medicine only on visible spots leaves new ones untreated.
How to get rid of acne on face?
Acne on the face is treated with a thin layer of one acne ingredient over the whole area that breaks out, such as the forehead, nose and chin, according to the American Academy of Dermatology. Wash twice a day with a gentle cleanser and your fingertips, use products labeled non-comedogenic, and wear SPF 30 sunscreen. The AAD says to expect fewer breakouts in 4 to 8 weeks.
How to get rid of acne that won't go away?
Acne that will not go away after 4 to 6 weeks of one treatment may need a second product that works on a different cause, the American Academy of Dermatology says. If it still has not cleared, see a doctor. The UK NICE guideline advises considering a dermatologist referral for mild to moderate acne that has not responded to two completed 12-week courses of treatment.
How to get rid of acne completely?
Clearing acne completely takes 3 to 4 months of steady treatment in most cases, according to the American Academy of Dermatology. The AAD's adult acne guidance puts clearing at 16 weeks after starting a medicine that works. For severe acne, it says 85 percent of patients see permanent clearing after one course of isotretinoin, a prescription pill that takes four to five months.
How to get rid of acne as a teenager?
Teen acne is treated with the same proven ingredients as adult acne, and the 2024 American Academy of Dermatology guideline covers people aged 9 and older. Adapalene 0.1 percent gel is FDA approved without a prescription for ages 12 and up. Start one product or the adapalene and benzoyl peroxide pair, use a thin layer on the whole area, and see a doctor for deep, painful or scarring acne.
How to get rid of acne without medication?
Mild acne can improve with habits alone: washing twice a day and after sweating, no scrubbing, keeping hands off, using non-comedogenic products and removing makeup before bed, all advised by the American Academy of Dermatology. Tea tree oil has only a small amount of research behind it, says the US National Center for Complementary and Integrative Health. Most acne still needs an acne treatment to clear.
How to get rid of acne during pregnancy?
Acne during pregnancy should be treated with a doctor's advice, because the American Academy of Dermatology says some acne treatments sold without a prescription are not safe in pregnancy. The UK NICE guideline says topical retinoids, including adapalene, and tetracycline antibiotic pills should not be used during pregnancy. NICE lists a benzoyl peroxide and clindamycin gel as one that can be used with caution.
How to get rid of acne forever?
Acne can stay away long term with maintenance treatment after it clears. The American Academy of Dermatology says to keep using acne treatment once the skin clears, and says dermatologists may recommend a topical retinoid to keep skin clear. The UK NICE guideline suggests a combination of adapalene and benzoyl peroxide as a maintenance option, reviewed every 12 weeks.
What is the first step to get rid of acne?
The first step to get rid of acne is to look at which types of spots you have, because the American Academy of Dermatology says different types of acne often need different treatment. Blackheads and whiteheads respond to a retinoid such as adapalene, red pimples to benzoyl peroxide, and deep, painful lumps need a dermatologist. Then start the treatment and add nothing else new.
Sources
- Guidelines of care for the management of acne vulgaris (Journal of the American Academy of Dermatology, PubMed record)
- Acne vulgaris: management (NG198), Recommendations (National Institute for Health and Care Excellence (NICE))
- Acne: Diagnosis and treatment (American Academy of Dermatology)
- Adult acne treatment dermatologists recommend (American Academy of Dermatology)
- 9 things to try when acne won't clear (American Academy of Dermatology)
- 10 skin care habits that can worsen acne (American Academy of Dermatology)
- 6 skin care habits that can clear acne (American Academy of Dermatology)
- How to treat different types of acne (American Academy of Dermatology)
- What can clear severe acne? (American Academy of Dermatology)
- 21 CFR Part 333 Subpart D, Topical Acne Drug Products (Electronic Code of Federal Regulations, for the FDA)
- Differin Gel (adapalene), 0.1%, supplement approval letter, NDA 20380/S-010 (FDA Center for Drug Evaluation and Research)
- DIFFERIN (adapalene) gel, Human OTC Drug Label (DailyMed, U.S. National Library of Medicine (label: Galderma Laboratories, L.P.))
- Acne (NHS)
- Benzoyl peroxide (NHS)
- Acne scars: What causes them? (American Academy of Dermatology)
- Tea Tree Oil: Usefulness and Safety (National Center for Complementary and Integrative Health (NIH))
- Moisturizer: Why you may need it if you have acne (American Academy of Dermatology)
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Get my free acne scoreSkinli gives simple tips for skin with pimples. It is not a doctor. It cannot tell you what is wrong the way a doctor can. If your pimples hurt, are deep under the skin, are getting worse, or will not go away, see a doctor.